1H and 13C NMR spectra of condensed benzimidazole and imidazobenzodiazepines

Loại tài liệu:

Article

Tác giả:

El-Kihel, A.

Đề mục:

Arabian Journal of Chemistry

Nhà xuất bản:

Elsevier Ltd.

Ngày xuất bản:

October 2012

Định dạng:

pdf

Nguồn gốc:

Arabian Journal of Chemistry, Volume 5, Issue 4, October 2012, Pages 523-526

Ngôn ngữ:

eng

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Lượt tải:

Nội dung

Benzimidazoles are heterocyclic compounds that have awakened great interest during the last few years because of their proven biological activity as antiviral, antimicrobial, and antitumoral agents. For this reason, the development of a systematic NMR study of condensed benzimidazole compounds constitutes a significant tool in understanding the molecular dynamics and the structural parameters that govern their behavior. The 1H and 13C NMR spectra of new imidazobenzodiazepines were investigated. Based on the study of NMR chemical shifts, we discuss the environmental effect of the nucleus 13C. The correlation 1H–13C proved to be a useful method for distinguishing the assignment of carbon.

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1H and 13C NMR spectra of condensed benzimidazole and imidazobenzodiazepines

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