Stability and thermophysical properties of azithromycin dihydrate

Loại tài liệu:

Article

Tác giả:

Timoumi, S.

Đề mục:

Arabian Journal of Chemistry

Nhà xuất bản:

Elsevier Ltd.

Ngày xuất bản:

April 2014

Định dạng:

pdf

Nguồn gốc:

Arabian Journal of Chemistry, Volume 7, Issue 2, April 2014, Pages 189-195

Ngôn ngữ:

eng

Lượt xem:

Lượt tải:

Nội dung

The aim of this paper was to describe the temperature effect on the stability and the thermophysical properties of azithromycin (AZ). First, the density, the heat capacity and the solubility of original (commercial) AZ were determined. Second, the original samples were heated at 50 °C and 80 °C and their PLM, DSC, TGA and XRD data were compared to those of the original AZ. According to our results, the original AZ was a dihydrate which converted to anhydrate when heated up to 80 °C. The dehydration induced a change of crystal habit while the crystalline lattice remained unchanged.

Tập tin đính kèm

Loại file Tên file Dung lượng Chi tiết
201402AJC189-195.pdf 1388692 Kb Xem Tải

Stability and thermophysical properties of azithromycin dihydrate

THƯ VIỆN ĐẠI HỌC KHOA HỌC HUẾ